About mAbsolute Kits
The mAbsolute kits, are low- and high-throughput glycan analysis kits, based on highly pure synthetic isotope-labeled internal standards for the absolute quantification of mAb glycosylation by MALDI-TOF MS. Minimal handling and time are required for sample preparation and within seconds, all relevant glycans of a deglycosylated mAb sample are quantified by comparison of MALDI profiles with the corresponding internal reference standards.
mAbsolute kits have been optimized for the MALDI-TOF based absolute glycan quantification using Bruker Autoflex and UltrafleXtreme III equipments. Validation is on-going for the application of the kits to different MALDI-TOF instruments and to other mass spectrometry techniques.
Video shows how to proceed to analyze glycan content of mAb using mAbsolute Kit.