CarboQuant standards

CarboQuant standards are patented synthetic¹³C-labeled N-glycans, produced entirely in our laboratory for use as internal standards in absolute glycan quantification by mass spectrometry. They are available as single standards for glycan analysis.

Absolute Glycan Quantification by MS using Stable Isotope Labeled Glycan Standards

> 95% pure
Fully characterized by MS and NMR
Show up to 8 Dalton mass increments. No overlap between the analyte and standard peaks.
All N-acetylglucosamines are labeled
Quantified internal standards (qNMR )
Broad coverage of N-glycan structures

Applications

Use of internal glycan standards to improve your glycan analysis workflow
Improve your method robustness with internal glycan standards
Quantify individual glycans in biofluids like any other metabolite
Use MALDI-TOF MS to generate quantitative glycan profiles in biomarker studies and biopharmaceutical research, with very fast sample preparation and acquisition

Field Applications for CarboQuant standards

Glycobiology

Rapid Absolute Glycan Quantification
Measure of glycan recovery for in-sample preparation
Internal standards for the quantitative glycan profiling by MALDI-TOF MS

Biopharmaceutical development

Rapid high-throughput glycan analysis in clone selection and process development
Quality control
Biosimilar optimization

Clinical Chemistry Biomarkers

Measure glycan levels in serum samples with picomole precision
Establish cut-off values for glycan biomarkers
Quantify aberrant glycosylation in cancer samples
Internal performance calibrants for method transfer and multiple laboratory studies

Designed for consistency, reproducibility and precision, CarboQuant expands the possibilities of quantitative glycomics — including challenging applications and analysis.