Diabetes

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Diabetes

Diabetes Biomarkers

Increasing levels

  • Severity and duration of glucose dysregulation in individuals can be estimated by monitoring the levels of O-GlcNAc simultaneously at specific sites on several key proteins in erythrocytes. Increase in antenna fucosylation of AGP in plasma from patients with Type 1 Diabetes Mellitus.
  • Glycan Standard 13C Biantennary A1(3) (Sial α-2,3)
  • Glycan Standard 13C Tetraantennary A4-G1a
  • Bis α-2,6-sialylated biantennary glycopeptide from egg yolk
  • Bis α-2,3-sialylated, galactosylated biantennary glycopeptide

References:
[34] Zihao Wang, et al., “Site-Specific GlcNAcylation of Human Erythrocyte Proteins“, Diabetes 2009, 59, 309.