Gastric Cancer Biomarkers
Increasing levels
- Increased levels of triantennary glycans carrying 2,6-linked sialic acids, and trisialylated triantennary glycans carrying sialyl Lewis X.
Gastric Cancer Biomarkers
Decreasing levels
- Decreased levels of fucosylated non- and mono-sialylated glycans.
- Decreased levels of biantennary asialo monogalactosylated glycans, and triantennary glycans carrying 2,3-linked sialic acids.
References:
[7] J. Bones, et al., Ultra performance liquid chromatographic profiling of serum N-glycans for fast and efficient identification of cancer associated alterations in glycosylation, Anal. Chem. 82 (2010) 10208–10215.
[8] J. Bones, et al., Glycomic and glycoproteomic analysis of serum from patients with stomach cancer reveals potential markers arising from host defence response mechanisms, J. Proteome Res. 10 (2011) 1246–1265.